Objective: This study investigated the relationship between glycemic markers and functional outcomes and examined the effects of occupational therapy on these outcomes in patients with subacute ischemic stroke. Methods: Thirteen patients with ischemic stroke were recruited. They received one-on-one occupational therapy for 4 weeks. Outcome measures included the modified Rankin Scale (mRS), Fugl-Meyer Assessment (FMA), Functional Independence Measure (FIM), and Stroke Impact Scale (SIS). Glycemic markers were levels of fasting blood glucose and glycosylated hemoglobin (HbA1c). Before and after the intervention, all outcome measures were administered to the participants. Results: Aftertherapy, a signi cant correlation of the mRS with blood glucose (rho = .72, p < .05) represents less disability related to lower level of the marker. Baseline blood glucose was significantly correlated with post-treatment scores on the mRS and FIM (rho = .60 and –.70; p < .05), which indicates its potential value in predicting disability outcomes. After therapy, all functional outcomes were significantly improved (p < .05). There was a significant decrease on the HbA1c level after therapy (p = .01). Conclusion: Based on the preliminary results, lower blood glucose levels were significantly associated with improved disability outcomes in patients which suggests that glycemic status could be monitored along with functional outcomes in stroke rehabilitation process. Further research with a large sample is needed to validate thesendings.